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doi: 10.3390/ijms26020776 85 RaoXAllisonDBFlightRMLinPHeDLiZet al

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Most substitutions of I178 4.60 , L181 4.63 , and F286 6.58 with alanine or polar and charged amino acids (Ser, Asp, or Lys) display dramatically diminished receptor activation compared with wild-type (WT) ghrelin receptor (Fig

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