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Paul Coates, former director of the Office of Dietary Supplements at the National Institutes of Health, reviewed many of the scientific studies on Protandim, including the one demonstrating a 7% increase in lifespan for male mice, and said he found them to be largely well designed, if small in scope

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The vitamin is also essential for DNA synthesis and red blood cell formation, meaning deficiency can have wide-ranging effects beyond the nervous system, including fatigue and cognitive difficulties