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The formulation magnesium, calcium, B vitamins including B12 and B6, and high-dose vitamin C addresses the widespread nutritional deficiencies that directly accelerate biological ageing in the Indian population

This essential coenzyme of ThDP-dependent enzymes is absolutely necessary not only for oxidative glucose metabolism, but also for coupling metabolic pathways of carbohydrates and amino acids, as well as for controlling de novo synthesis of major neurotransmitters, ACh and glutamate, from glucose

Science 287 , 12651269 (2000)

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Both choline and methionine are a source of methyl groups for the one-carbon transmethylation pathway and serve hepato-protective functions