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doi:10.3389/fphar.2022.879020

In dermatological contexts, the most clinically relevant gene targets include: COL1A1 and COL3A1 upregulation increases procollagen type I and III synthesis, directly counteracting age-related collagen depletion

The risk of pancreatitis can be minimized by addressing and mitigating risk factors from previous episodes, regulating the rate of weight loss by adjusting the GLP-1 receptor agonist dose and the content and frequency of meals, closely monitoring patients during GLP-1 receptor agonist therapy, and implementing appropriate precautionary measures

In the U.S., its not FDA-approved for human use and sold as a research compound

It is estimated that 45 million adult Americans set a goal to lose weight every year