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One study found that when women with overweight or obesity lost weight, their estrogen and testosterone levels dropped significantly

The results showed that retatrutide at the 8 mg dose reduced total body fat mass by 26.1% at 36 weeks, while the proportion of lean mass lost relative to total weight lost was consistent with other weight loss treatments

The agency said it would consider all responses before a final decision is made by June 2024

From our data, it seems clear that retatrutide can act in cardiomyocytes in the HAP

But obesity is a chronic disease requiring years of treatment, not months

Ribeiro-Silva JC, Tavares CAM, Girardi ACC