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95% CI, 0.27-0.92)

Some foods that increase GLP-1 due to their healthy fats include: avocados nuts olive oil fatty fish, like salmon Dark chocolate is rich in flavonoids that may support GLP-1 activity

Completed and Ongoing Trials Several completed clinical trials have shown retatrutide has better weight loss than existing therapies

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Why Orforglipron Matters Unlike peptide-based GLP-1 therapies, Orforglipron is a **small-molecule oral drug**, eliminating the need for weekly injections