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Whereas apathetic depression in K3 was the least common, with statistically significant differences from K1, it was the classic dreary and dreary-inhibited depression, typical of middle-aged patients, was more often noted, albeit not significantly different from K1 and K2 clusters

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On the other hand, gastrointestinal disturbances are critical early indicators of severe thiamine deficiency causing pediatric Wernicke Encephalopathy (54)

Origlia N, Migliori M, Panichi V, Filippi C, Bertelli A, Carpi A, Giovannini L: Protective effect of L-propionylcarnitine in chronic cyclosporine-a induced nephrotoxicity