It is administered as a subcutaneous injection (just under the skin)
Similarly, liraglutide for diabetes (Victoza) starts at 0.6 mg daily, escalating to 1.2 mg and potentially 1.8 mg if needed, while liraglutide for weight management (Saxenda) follows a schedule from 0.6 mg to 3.0 mg daily (via 1.2 mg, 1.8 mg, and 2.4 mg steps)
Korol SV, Jin Z, Babateen O, Birnir B
The 2.4 mg group lost the most weight, which means that among adults suffering from overweight or obesity and T2DM, SMG 2.4 mg once a week has achieved significant clinically significant weight loss (99)
Clinical implication The updated FDA labeling for liraglutide and semaglutide highlights the importance of monitoring depressive symptoms or suicidal thoughts, suggesting treatment discontinuation if such ideations occur [87,88]
Compounded retatrutide typically comes in 10mg or 20mg vials