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doi: 10.1007/s12016-025-09038-1 Summary Keywords gut microbiota, Porphyromonas gingivalis, Fusobacterium nucleatum, Streptococcus mutans, systemic disease, oral microbiota Citation Gan G, Chen R, Zheng P, Long K, Cheng KKY, Sulaiman JE and Huang X (2026) Oral pathogens meet the gut microbiome: new mechanistic insights on systemic disease