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In addition to using Met as a source of reducing power to sustain redox homeostasis, TrxR1/Gsr-null livers require Met and Met-derived Cys for protein translation and for synthesis of other S -containing metabolites [112], including S -adenosyl methionine (SAM
Angelova P
Pathogens and the host immune response collectively dysregulate intracellular iron metabolism and ROS levels, ultimately leading to membrane damage via lipid peroxidation ( In this review, we present a comprehensive overview of ferroptosis in pathogen-related infections, discussing its implications for disease progression and treatment
& Tappel, A
CBO points out that the studies we have on this topic rely on correlations between [body mass index (BMI)] and health conditions and between health conditions and health care spending, which may or may not be driven by a causal relationship. As CBO notes, there is a correlation between higher BMIs and higher health care spending
J Biol Chem 284:436445
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