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Management of obesity

No First-Pass Effect : Like injections, nasal delivery skips the livers first-pass metabolism

Ask how follow ups work and what changes would signal a dosage adjustment

Seek immediate medical attention (call 999 or attend A&E) if you have severe pain uncontrolled by over-the-counter analgesia, high fever (above 38C) with loin pain, inability to pass urine, or persistent vomiting preventing fluid intake

Research on GLP-1 receptor agonists (the parent class of tirzepatide) shows that nutrient deficiencies are rare during treatment, but they can develop over time if baseline levels are low or if intake decreases due to reduced appetite

universal salt iodisation) need to ensure that such fortification is introduced very cautiously