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However, its poor permeability and foul odor limit its use in skin applications

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GABA exerts its effects by binding to two distinct receptors, GABA-A (GABA A ) and GABA-B (GABA B ) that are members of the ion channel (ionotropic) receptors

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10.1016/j.plipres.2010.09.001 52 Hernandez-RodriguezM.ClementeC

A comparative review on heart ion channels, action potentials and electrocardiogram in rodents and humans: extrapolation of experimental insights to clinic