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Collingridge GL, Lester RA (1989) Excitatory amino acid receptors in the vertebrate central nervous system

Under stress or diseased conditions (e.g., heat stress, infection, obesity, diabetes, and cancer), taurine synthesis in the body may be impaired due to the suboptimal function of liver and the reduced availability of the amino acid precursors

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The problem is that the crystals are often extensive, and track back to the bone, so there is not a good healing surface once the tophus is removed

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Although the electron density at the distal end of the octanoyl group was not visible in the three structures, it undoubtedly resides within Cavity II