However, we have tried to make a more equitable comparison by choosing similar timepoints across all drugs (when available) and summarise them below
Curr Opin Gastroenterol 2017
Beyond direct antioxidant activity, GSH functions as an obligatory cofactor for a family of enzyme systems that are central to cellular defence: glutathione peroxidases (GPx), which reduce peroxides and lipid hydroperoxides using GSH as the reducing substrate
Mutation of the acidic residues in the COPII binding region greatly reduced cell surface expression, with S protein accumulating in the ER, indicating that these residues direct efficient egress of the newly made S protein out of the ER and into the secretory pathway (Fig
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