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Following synthesis, the peptide undergoes purification using high-performance liquid chromatography (HPLC) to verify chemical purity and remove synthesis byproducts or truncated peptide fragments

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In this case, overall assessment (WoE) of the general biological plausibility and of the empirical support of KERs was considered as high for this AOP, as well as essentiality, once for this criterion the first four KEs that trigger the AO are also classified as such

You can also report side effects directly via the Yellow Card Scheme at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store