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Unlike semaglutide, tirzepatide is a dual receptor agonist targeting both GLP1R and GIPR
Similarly, in a cross-sectional study by Johnson et al., analysis of 3-day food records in individuals using GLP-1 RA for at least one month showed that 75% of participants reported having increased their protein intake after treatment, yet only 43% achieved the recommended intake of 1.2 g/kg/day
340 calories, 30g protein
Based on this behavioral parity principle, arm-specific discontinuation rates were recalculated so that the post-semaglutide discontinuation probability of stopping D&E after discontinuing semaglutide was identical to that of patients in the D&E group
That level of uncertainty demands serious attention
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