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As such they attract molecules containing a Src-homolgy 2 (SH2) domain (several docking sites for phosphorylated tyrosines)

Wu and Ng reported in 1993 that a synthetic fragment corresponding to residues 177 to 191 of hGH reproduced the antilipogenic activity of the whole molecule in isolated rat adipose tissue, which framed the C-terminal region as a candidate research tool

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This issue, however, was rekindled and became a subject of debate with the 1996 approval by the US FDA of mandatory folic acid fortification of staple food products for the prevention of neural tube defectaffected pregnancies (13)