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JAMA , 295(17):2003-2017

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Thus, we next designed and synthesized a set of eight compounds that contain an aromatic aldehyde in place of the aliphatic amine of UNC8732, with the expectation that these aromatic aldehydes would be more stable in a cellular environment and would be easier to synthesize than their aliphatic counterparts, while potentially maintaining the ability to engage C326 in a similar reversible covalent fashion

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Additionally, urbanization, a growing middle-class population, and lifestyle changes are further driving adoption and market growth in the region