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de Goede P, Wefers J, Brombacher EC, Schrauwen P, Kalsbeek A
Cycle Length Considerations Clinical trials ran for 48 weeks with participants still losing weight at study conclusion, suggesting longer treatment periods may yield additional benefits
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The mechanisms that may contribute to the induction of oxidative damage in diabetic patients include hyperglycemia-induced glucose auto-oxidation, non-enzymatic glycation of proteins and lipids, increased sorbitol pathway activity, oxidation of AGEs, and formation of prostaglandin H2 (PGH2) [311]
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doi: 10.1016/j.mito.2015.06.002
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