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This premium is directly tied to its status as a triple agonist. While semaglutide only mimics one hormone and tirzepatide mimics two, retatrutides addition of the glucagon pathway increases energy expenditure in research models, making it a highly valuedand therefore costlyasset

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GLP-1 medications such as Ozempic, Wegovy, Mounjaro, and Zepbound continue to grow in popularity among patients in Long Island and throughout New York

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The SURPASS program demonstrated HbA1c reductions of 2.0-2.3% at the 15mg dose, with many participants achieving HbA1c below 5.7% (the threshold for normal blood sugar)

The trial also reported better retention rates, with less discontinuation due to side effects than a placebo for lower doses