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Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, Towheed T, Welch V, Wells G, Tugwell P, American College of R (2012) American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee

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Among these two, Mazdutide might still have more room to maneuver, including higher dosing explored in Phase 2 (up to 9 mg) and adopting a more conservative titration strategy (GLORY-1 trial titrated only two doses over 8 weeks)

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Research on managing type 2 diabetes and metabolic health consistently points to a diet built around high-fiber foods, quality protein, and healthy fats while limiting saturated fat and refined carbohydrates