Moreover, non-pharmacological interventions, like peritumoral electroacupuncture, have also been demonstrated to increase tumor sensitivity to chemotherapeutic agents by inhibiting GLO1, further strengthening the potential of GLO1 as a targeted therapeutic indicator (159)
Effect of the mGluR5-NAM basimglurant on behavior in adolescents and adults with fragile X syndrome in a randomized, double-blind, placebo-controlled trial: fragXis phase 2 results
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Recently, investigations indicated that protegrin-derived SynB1 CPPs, and Antennapedia homeodomain-derived penetratin (antp), could increase the doxorubicin delivery (an anticancer drug) across the BBB, which indicates their ability to treat glioblastoma [110, 111]
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