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Recent studies using both in vitro and in vivo models indicate that glycyrrhizin directly targets and binds to the RNA-binding protein CUG-binding protein 1(CUGBP1), activating the Interferon (IFN)-/Signal Transducer and Activator of Transcription (STAT)1/Smad7 signaling pathway and thereby inhibiting HSC activation, ultimately exerting anti-fibrotic effects (Wu et al., 2016)

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SCD: sickle cell disease (HbSS and sickle- 0 -thalassemia genotypes only)

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Osteoarthritis: pathobiology-targets and ways for therapeutic intervention

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(NPR reached out to Noah Jay through his TikTok and Instagram accounts for comment and to ask if he receives any income from the peptide sales, but did not receive a reply.) But there are risks when using substances that aren't approved by the Food and Drug Administration for human use

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Hrmova M, Hussain SS (2021) Plant transcription factors involved in drought and associated stresses

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