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The receptor is a glycoprotein with an N-terminal extracellular signal peptide and, like all G protein-coupled receptors, a seven-transmembrane helix domain [6]

Modulation of the mechanical responses of synovial fibroblasts by osteoarthritis-associated inflammatory stressors

The antibodies simply do not recognize peptide structures

STOLLEY, P.D., SOPER, K.A., GALLOWAY, S.M., NICHOLS, W.W., NORMAN, S.A., & WOLMAN, S.R