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Aged mice (22 months, equivalent to roughly 65 to 70 human years) treated with MOTS-c three times per week doubled their running capacity on treadmill tests

For example, in STEP 1 in the placebo group, the sample reported for the week 68 percentage change from baseline in weight was 577 patients, which is 12% less than the original baseline sample of 655, despite the fact that 7% of patients were reported as having withdrawn from the study in this group, and 22% were reported as having stopped treatment

The study is published in Nature Communications