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During these early experiments, Pickart observed that plasma from younger individuals appeared to stimulate regenerative processes more effectively than plasma from older adults

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Chronic persistent hypoxia is recurrent in chronic lung diseases where O 2 levels remain constantly low, while chronic IH is characteristic of obstructive sleep apnea, characterized by an intermittent pattern of episodes of hypoxia and reoxygenation [133]

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Li P, Jiang M, Li K, Li H, Zhou Y, Xiao X, et al