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Most were skin-related symptoms, but anaphylaxis is possible with IV NAC.[ref] Some people also report gastrointestinal side effects with NAC

In the sym40-1 mutant, the amount of GSH label was higher in juvenile bacteroids than in wild-type ones (Figure 4D and Table 2)

[6] [7] Other potential side effects during the first weeks include injection site reactions (erythema, pruritus, or mild discomfort), fatigue, and headache