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JMF4073, containing a fluoride substitution at the C-position of the pyridine ring, has the lowest IC50 value and higher solubility, as indicated by the clogP value (Fig

Combining HDAC inhibition with TNF--related apoptosis-inducing ligands further enhances its anticancer efficacy

Energy Metabolism and Metabolic Pathway Probing Due to MC4Rs role in energy homeostasis, MT1 is used in animal studies to assess receptor-linked regulation of lipid metabolism, substrate oxidation, and body-weight regulation under experimental diets or stressors

Limit of detection and limit of quantification The LOD and LOQ were determined using the data obtained from the linearity analysis as mentioned in Tables 13, 14 and 15

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