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Remove the needle from the patients arm, have them hold the cotton ball with pressure

That chemistry makes it hydrophilic and poorly suited for partitioning into the lipid-rich stratum corneum

Once breakdown starts, a protein called intrinsic factor, released by parietal cells in the stomach, binds to vitamin B12 in the duodenum (small intestine) and forms a B12-intrinsic factor complex that allows B12 to be absorbed in the terminal portion of the small intestine

However, twice-weekly dosing lacks formal study support and FDA approval

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