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GLP-1 medications are often well tolerated, but side effects can happen, especially as the body adjusts or when dosage increases

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Shedding of the endothelial glycocalyx in patients undergoing major vascular surgery with global and regional ischemia

Muratori, F

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Some patients experience mild head discomfort with each dose increase, but these episodes are typically shorter and less intense than initial treatment headaches, resolving within three to five days