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NAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in all living cells, playing a central role in cellular energy metabolism , DNA repair , and mitochondrial function
Many of the interventions we discuss can be potentially dangerous if done without proper clinical supervision
Since only approximately 60% of the patients at our centre that were prescribed or considered eligible for GLP1-RA therapy for weight regain after bariatric surgery were included in the present analysis, the weight lowering effect might be overestimated as patients who stopped treatment because of adverse side effects are not adequately represented
While multiple clinical trials and population-based studies have established the safety profile of GLP-1RAs, continued vigilance regarding the association between GLP-1RA therapy and pancreatic cancer risk remains imperative in clinical practice, given the potential for low-grade chronic pancreatitis to induce pancreatic cancer
Second, although we employed PSM to balance covariates between treated and control groups, residual confounding could not be completely avoided