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3 Mammalian CHAC2: defining its role in glutathione homeostasis, cancer progression and stem cell fate In addition to CHAC1, which is found exclusively in higher eukaryotes, organisms from bacteria to mammals possess a CHAC2 enzyme that exhibits a highly similar glutathione-specific GCT activity (Kaur et al., 2017)
Screening for high homocysteine in individuals with early signs of age-related cognitive impairment may be warranted because B-vitamin supplementation may slow the rate of brain atrophy in this population
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Cancer cells and normal cells potentially use different food sources, and we discovered how cancer cells, specifically, break down this antioxidant and use it as fuel." Isaac Harris, PhD, Wilmot Cancer Institute, University of Rochester The new role for glutathione is notable, Harris said, because until now, most scientists who study glutathione have focused on the way it can prevent or repair cell damage, rather than its ability to feed cancer cells
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