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Enterohormonal changes after digestive adaptation: five-year results of a surgical proposal to treat obesity and associated diseases
Although the glucoregulatory actions of metformin on glucose tolerance and inhibition of food intake are not completely eliminated in incretin receptor knockout mice, the extent to which metformin exerts its metabolic actions in part through incretin receptors in more severely diabetic models that are resistant to suppression of hepatic glucose production merits further exploration
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Following his finding in Mutt's laboratory, Brown spent a sabbatical year at the University of Gttingen in the department of Werner Creutzfeldt, an expert in gastrointestinal endocrinology and strong proponent of the existence of the incretin concept
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