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In the context of lipid metabolism, targeting pathways such as ether lipid synthesis, fatty acid synthase (FASN), or the ACLY/ACC axis has been shown to induce mitochondrial stress and ROS accumulation, thereby enhancing apoptotic responses [144]

CDPKs combine sensory and effector functions, while CaMs and CBLs act as relays modulating downstream kinase and phosphatase cascades

(DOCX) Acknowledgments The study was supported by a research grant from Department of Science and Technology, New Delhi, India (SB/SO/BB/009/2013)

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Intracellular calcium stores are mobilized, and protein kinase C is activated by these second messengers, leading to downstream gene activation and TSH transcription

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