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Significant barriers still exist despite established safety profiles, such as high costs that restrict access worldwide, a lack of predictive biomarkers for treatment response, a lack of knowledge about the mechanistics of gut microbiota interactions, and an incomplete understanding of long-term safety, particularly with regard to thyroid and pancreatic effects

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P., Jdar, E., Tran, N., McCrimmon, R

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Archived from the original on 19 December 2012

Patients taking Mounjaro who require hospitalisation or surgery should inform their healthcare team about their medication, as temporary adjustments may be necessary according to local anaesthesia and surgical policies