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Interestingly, in cells that lack PERK, peroxides such as H 2 O 2 accumulate after ER stress

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In addition, 18 F-FDG PET imaging allowed to show the presence of extensive and durable hypometabolism in several brain regions of long COVID patients (176, 177), in particular in the pons and the right amygdala (178)

2.7 Preparation of mitochondria and assay of enzyme activity The enzyme activity of three respiratory-chain complexes was quantified in the mitochondria of L-02 hepatocytes treated with CGA and in untreated cells, as previously described ( 2.8 Quantitative analysis of oxidized and reduced forms of glutathione (GSH) To detect GSH and GSSG (glutathione disulfide), two 200 L sample solutions were prepared