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No human safety data : The complete absence of human clinical trials means the safety profile, side effects, optimal dosing, and pharmacokinetics in humans are entirely unknown Animal-to-human translation is uncertain : Metabolic differences between mice and humans mean that the magnitude of effects (e.g., weight loss, grip strength improvement) may not translate

Its crucial to adhere to recommended cycle lengths (e.g., 30-60 days on, followed by an equal period off) to prevent this and maintain efficacy

Dosage typically ranges from 200400mcg per administration

Directions for use Horses: 5 - 10mL i.m

Patients should be informed of the pros and cons of oral versus parenteral therapy, and regardless of the form of treatment, those with pernicious anemia or malabsorption should be reminded of the need for lifelong replacement

As noted above, this may be particularly true of the peptides gastroprotective effects [9, 31]