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For more information, see our guide on GLP-1 use and pregnancy

Therefore, it is possible that the gut microbiota can impact intestinal nutrient-sensing mechanisms (Fig

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What you might notice: Mild appetite reduction, particularly in the 24 to 72 hours after injection Slight nausea, especially after eating large or fatty meals A subtle sense of fullness that arrives sooner than expected Some people notice absolutely nothing at this stage Weight change in week one is typically minimal, zero to two pounds