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Primary antibody (anti-GCSc 1:100 (SantaCruz, sc390811), anti-CD45 1:100 (Santa Cruz, sc1178), anti-F4/80 1:100 (Cell Signaling Technology, 70076), anti-DNA/RNA Damage 1:200 (Abcam, 62623), anti-NRF2 1:100 (Abcam, 31163) and anti-GGT1 1:200 (donated from M
Our previous study observed positive associations of plasma BCAAs to cartilage retention and physical performance in KOA patients [13]
Alterations in the normal function of excitatory amino acid carrier 1 affect cysteine transport and GSH synthesis impairing zinc homeostasis (the thiol group of GSH can function as a principal Zn 2+ chelator for the maintenance of Zn 2+ homeostasis in neurons) and oxidative stress, enhancing susceptibility to ischemia-induced neuronal cell death in the hippocampus (162164)
461 CITED2 also regulates p53 activity to promote AML, and therefore it can be a potential target for AML therapy
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