Cerebral pharmacokinetics and microdialysis To confirm that a peptide actually reaches its cerebral target, microdialysis remains the reference tool: Principle : insertion of a semi-permeable membrane probe in a target region (hippocampus, frontal cortex)
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The significant alleviation in A burden, anti-inflammatory and antioxidative effects, and enhanced synaptic transmission activity were also observed in the hippocampus
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Some patients experience mild side effects such as temporary redness, swelling, bruising, or tenderness at the injection site
