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Brain scan studies show that people with high self-motivation display greater dopamine activity in key brain regions[6 Trusted Source 2012 - The Journal of Neuroscience Dopaminergic Mechanisms of Individual Differences in Human Effort-Based Decision-Making ]

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Side effects with tirzepatide are primarily gastrointestinal, with cardiovascular effects being relatively modest

That said, preliminary evidence inspires interest and warrants attention for anyone considering dietary changes for a healthier lifestyle