The so-called polyglutamine (polyQ) toxicity leading to the neuronal loss and extensive injury of non-neuronal cells is mediated through mitochondria damage and includes the crucial role of the gut-brain axis and gut microbes in development and progression of neurological disorders
Gunjal VB, Thakare R, Chopra S, Reddy DS
Comparative example 2 Referring to the method of patent CN105154498A, boc-His (Boc) -Aib-OH dipeptide was used instead of Boc-His (Trt) -Aib-OH dipeptide in the present invention, and the other conditions were the same as in example 6
Science ., doi: 10.1126/science.ado5019.
[DOI] [PubMed] [Google Scholar] 229.Tudur E, Beiroa D, Porteiro B, Lpez M, Diguez C, Nogueiras R
This section applies to any and all claims by You, including, but not limited to, lost profits or revenues, consequential or punitive damages, negligence, strict liability, fraud, or torts of any kind