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With prescription GLP-1 medications like Ozempic and Wegovy costing $800-1,200 per month without insurance coverageand most insurers denying coverage for weight management indicationsconsumers are increasingly researching affordable alternatives

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Without one, muscle loss from weight loss cannot be cleanly separated from muscle loss from the drug. The few preclinical studies that have run this comparison, including the Langer 2026 data, show that the drug does not add incremental muscle loss beyond what matched weight loss produces

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Results vary, but patients often lose 5-10% of body weight over 3-6 months on Phentermine alongside diet and exercise