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Supplementation of vitamin B12 COMPOSITION Cyanocobalamin (Vitamin B12) 1mg/mL ACTIONS Supplementation of Vitamin B12 INDICATIONS Vitamin B12 supplement for the treatment of macrocytic anaemia in horses and dogs DOSAGE AND ADMINISTRATION Administer intramuscularly twice weekly or as directed by a veterinary surgeon

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Biotin deficiency can cause dry skin, brittle nails and hair, as well as hair loss

Increased reactive oxygen species production during reductive stress: The roles of mitochondrial glutathione and thioredoxin reductases

Severe loss of quality of life, due to symptoms such as debilitating fatigue, insomnia (B12 is required for synthesis of melatonin), mental illness, and neurological symptoms