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Such limitations make it difficult to distinguish true sensory modulation from conditioned aversion secondary to nausea or early satiety effects that are well documented across GLP-1RA trials (153, 157, 173, 180)
Pregnant women, individuals with a history of thyroid cancer or certain thyroid diseases, and those with a history of pancreatitis should steer clear of Wegovy
The glucagon receptor arm the feature that distinguishes retatrutide from earlier-generation incretin compounds drives hepatic glucose metabolism, lipid oxidation, and energy expenditure effects, all absent from GLP-1 mono-agonists and dual GLP-1/GIP agonists
