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Grigoletto Fernandes et al., 2020
Experimental studies have also shown that coronaviruses induce downregulation of antioxidant genes such as Nrf2 in combination with an upregulation of oxidative stress genes like myeloperoxidase that may contribute to both increased viral replication and inflammation
The chance of full recovery has been estimated to be only 5% (28) as most patients do not regain their full pre-ME/CFS function
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