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In contrast, intravenous glutathione raises serious safety concerns, including the risk of anaphylaxis and hepatotoxicity, compounded by the lack of standardized protocols and rigorous clinical studies

Retrieved 2007-12-20

187 A study also shows that purpurin and its analog, R162, acting as mixed model inhibitors of GDH1, inhibit GDH1 activity, elevate ROS levels and thus attenuate cancer cell proliferation

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