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hCiPSC-NSCs Treatment Modulates Gut Microbiota Composition Analysis of gut microbiota composition across multiple taxonomic levels revealed distinct profiles among the Control, VPA-induced ASD model (VPA-ASD), and hCiPSC-treated (hCiPSCs) groups (Fig

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It is thought that over time, the disease shifts from an early hypermetabolic state to a hypometabolic state with decreased metabolites (251) and reduced energy production (59), correlating with patient clinical profiles (185)

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GLP-1R agonists cannot be currently recommended as targeted approaches for MASH but should be administered for their indications (T2D, obesity)