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Dec 26 2021;12(12):CD010117

In the clinical progression of Parkinsons, lower levels of glutathione relate to the increased severity of the disease

Most cases can be safely managed at home with hydration and symptom monitoring, but professional guidance is essential to rule out complications

Therefore, Y1R agonists and Y2R antagonists (since Y2R acts as an autoreceptor) seem promising for the treatment of heavy drinking that is driven by anxiety or negative reinforcement