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What the Studies Actually Showed: Preclinical Data Study 1: Fat and Liver Mass Drop Far Faster Than Muscle In diet-induced obese mice treated with tirzepatide (the dual GLP-1/GIP agonist in Mounjaro and Zepbound) for 14 days, researchers found a 73% reduction in body fat and only a 13% reduction in LBM

Methods A protocol was developed for this systematic review following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines

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Drugs in clinical trials and their outcomes Overview of phase IIII clinical trials In recent decades, numerous pharmacological agents have progressed into phase IIII clinical trials for spontaneous ICH

P., Mettang, T., Pauli-Magnus, C., Weber, J., and Kuhlmann, U